The Functional Effects for the Prevention and Treatment on Hair Loss from Astringent Persimmon Fruit Extracts

This study investigated the effects of astringent persimmon fruit extracts on hair growth in genetically predisposed balding Black mice. The research found that applying a water extract of astringent persimmon fruit (10 mg/mouse/day) significantly increased the hair existing area and hair length compared to the vehicle-treated control group (P > 0.001). Histological assessments showed a notable increase in the number of hair follicles in the persimmon-treated group. These results suggested that topical application of astringent persimmon fruit could promote hair growth by extending the hair existing area and increasing hair length, indicating a prolonged anagen phase.