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research Safety and efficacy of advanced and targeted acid α-glucosidase (AT-GAA) (ATB200/AT2221) in ERT-switch nonambulatory patients with Pompe disease: preliminary results from the ATB200-02 trial

3 citations , February 2019 in “Molecular genetics and metabolism”

The combination of tadalafil and finasteride improves urinary symptoms and erectile function in men with enlarged prostates.

research Cervi Parvum Cornu complex for men with lower urinary tract symptoms: a multicenter, randomized, double-blind, placebo-controlled trial

1 citations , September 2023 in “Prostate International”

Cervi Parvum Cornu complex improved urinary symptoms in men without major side effects.

research PD49-03 IS TADALAFIL ASSOCIATED WITH DECREASED RISK OF MAJOR ADVERSE CARDIAC EVENTS OR VENOUS THROMBOEMBOLISM IN MEN WITH LOWER URINARY TRACT SYMPTOMS?

April 2022

Tadalafil may reduce the risk of major heart events and blood clots in men with urinary symptoms.

research Guideline for the primary care management of male lower urinary tract symptoms

97 citations , May 2004 in “British Journal of Urology”

Dual therapy with specific medications can help manage male urinary symptoms and reduce side effects.

research Fixed-dose combination PRO 160/120 of sabal and urtica extracts improves nocturia in men with LUTS suggestive of BPH: re-evaluation of four controlled clinical studies

14 citations , June 2014 in “World Journal of Urology”

The herbal combination of saw palmetto and stinging nettle reduces nighttime urination in men with urinary issues.

research Most recent findings of curative drugs for lower urinary tract symptoms in clinical practice

January 2019 in “Nihon Yakuri Gakkai nenkai yoshishu”

Current treatments for lower urinary tract symptoms include α1-blockers, 5ARIs, PDE5 inhibitors, anticholinergic agents, and β3-adrenergic receptor agonists.

research Sebaceous glands changes following topical application of citral

14 citations , September 1983 in “Acta Dermato Venereologica”

Citral increases sebaceous gland activity in male rats.

research titanflow

March 2026

Titanflow improves male urinary health by strengthening the detrusor muscle and enhancing urine flow.

research Cytotoxic and antioxidant effect of the ethanolic extract of Citrullus colocynthis L. plant fruit

3 citations , May 2021 in “Genetics and Biodiversity Journal”

Citrullus colocynthis fruit extract has strong antioxidant and cancer-fighting potential.

research Solubilization and Solid‐State Characterization of a Poorly Soluble 5‐α Reductase Inhibitor

January 2004 in “Drug Development and Industrial Pharmacy”

GI197111X is best dissolved in Capmul MCM for trials.

research Impact of Cernitin™ on induced chronic prostatitis in animal model for understanding management of lower urinary tract symptoms

1 citations , March 2021 in “Phytomedicine plus”

Cernitin™, a pollen extract, was found to significantly reduce pain and inflammation in rats with chronic prostatitis, suggesting it could be a useful alternative to certain anti-inflammatory drugs.

research Fesoterodine: Pharmacological properties and clinical implications

5 citations , May 2018 in “European journal of pharmacology”

Fesoterodine is effective and safe for elderly patients with overactive bladder.

research GC-MS analysis and phytochemical screening of methanolic fruit extract of Citrullus colocynthis (L.) Schrad

January 2019 in “Journal of Pharmacognosy and Phytochemistry”

The methanolic fruit extract of Citrullus colocynthis contains bioactive compounds that may support its use in traditional medicine and drug development.

research The synthesis of (−)-4-methyl-8-chloro-trans-1,2,3,4,4a,5,6,10b-octahydrobenzo-[f]-quinolin-3-one-[3-14C] (LY300502-14C]) via a circuitous route

3 citations , October 1994 in “Journal of Labelled Compounds and Radiopharmaceuticals”

Scientists made a carbon-14 labeled version of a drug with a 48% yield and over 99% purity.

research Effects of Lespedeza Cuneata aqueous extract on testosterone-induced prostatic hyperplasia

16 citations , January 2019 in “Pharmaceutical biology”

Lespedeza cuneata extract may help treat enlarged prostate.

research Pharmacological Approaches in Managing Symptomatic Relief of Benign Prostatic Hyperplasia: A Comprehensive Review

1 citations , December 2023 in “Curēus”

Tadalafil is effective for treating urinary symptoms in men with BPH.

Efficacy and Side Effects of Drugs Commonly Used for the Treatment of Lower Urinary Tract Symptoms Associated With Benign Prostatic Hyperplasia

research Efficacy and Side Effects of Drugs Commonly Used for the Treatment of Lower Urinary Tract Symptoms Associated With Benign Prostatic Hyperplasia

35 citations , May 2020 in “Frontiers in Pharmacology”

Different drugs for prostate-related urinary symptoms work but have various side effects, and treatment should be tailored to the individual.

research Citrullus colocynthis (L.) Schrad. (Cucurbitaceae)

4 citations , January 2020

Efficacy and Safety of a Proprietary Free Fatty Acid Rich Saw Palmetto Extract (USPlus® PRO) for Lower Urinary Tract Symptoms in Males: A Randomized, Double-Blind, Placebo-Controlled Trial

research Efficacy and Safety of a Proprietary Free Fatty Acid Rich Saw Palmetto Extract (USPlus^® PRO) for Lower Urinary Tract Symptoms in Males: A Randomized, Double-Blind, Placebo-Controlled Trial

January 2026 in “Food and Nutrition Sciences”

USPlus PRO saw palmetto extract improves urinary symptoms and is safe for men.

research Protolytic Equilibria of Cetirizine in the Presence of Micelle-Forming Surfactants

January 2025 in “Organics”

Micelles can change cetirizine's ionization, affecting its effectiveness in treatments.

research The Effect of Leonuri Herba alkaloids on Senile BPH (male and female hormone induced) model rats

4 citations , March 2017 in “Al-Mi’galaẗ al-sa'udiyaẗ lī-ulum al-ḥayaẗ”

Leonuri Herba alkaloids may help treat hormone-induced enlarged prostate in rats.

research Citrullus colocynthisas the Cause of Acute Rectorrhagia

9 citations , January 2013 in “Case reports in emergency medicine”

Eating Citrullus colocynthis can cause severe intestinal bleeding and damage.

research Evidence for the efficacy and safety of tadalafil and finasteride in combination for the treatment of lower urinary tract symptoms and erectile dysfunction in men with benign prostatic hyperplasia

14 citations , May 2016 in “Therapeutic advances in urology”

Taking tadalafil and finasteride together is safe and effective for treating urinary symptoms and erectile dysfunction in men with enlarged prostates.

research Drug–Drug Coamorphous System of Tadalafil and Finasteride for Enhanced Pharmaceutical Performance

December 2025 in “Molecular Pharmaceutics”

Combining tadalafil and finasteride improves their solubility and effectiveness.

research Drug–DrugCoamorphous System of Tadalafil andFinasteride for Enhanced Pharmaceutical Performance

December 2025 in “OPAL (Open@LaTrobe) (La Trobe University)”

A new combination of tadalafil and finasteride improves drug performance and stability.

research Biotransformation of tirilazad in human: 4. effect of finasteride on tirilazad clearance and reduced metabolite formation.

3 citations , November 1998 in “PubMed”

research MP09-16 5-ALPHA REDUCTASE INHIBITORS FOR MALE LOWER URINARY TRACT SYMPTOMS: A COCHRANE SYSTEMATIC REVIEW AND META-ANALYSIS

April 2017 in “The Journal of urology/The journal of urology”

5-alpha reductase inhibitors slightly reduce urinary symptoms and may lower surgery and acute retention risks in men.

research AB032. Development of new treatment modality for male infertility by using phytopharmaceuticals

September 2018 in “Translational andrology and urology”

MOTILIPERM may help treat male infertility by reducing stress in cells.

research Comparison of Different Alpha-blocker Combinations in Male Hypertensives with Refractory Lower Urinary Tract Symptoms

8 citations , January 2011 in “Korean Journal of Andrology”

The doxazosin plus tamsulosin combination improved symptoms effectively with fewer side effects.

research Effect of Citrullus coclocynthis Schrad on hair growth activity of albino rats

5 citations , January 2007

Citrullus colocynthis extracts may promote hair growth as effectively as minoxidil.

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