2 weeks before and after: Switched from oral minox to topical and added JXL-069/PP405-3HP Progress Pictures 4/8/2026
The user switched from oral minoxidil to topical minoxidil and added JXL-069/PP405-3HP, along with topical dutasteride, melatonin, and tretinoin. They also use low-level laser therapy (LLLT) but doubt its effectiveness.
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5 / 1000+ resultscommunity PP405 (Everychem 3HP) Anecdotes - Please assemble and share your story
PP405 (Everychem 3HP) may help with hair regrowth, with mixed user experiences. Users often combine it with minoxidil and finasteride, but there are concerns about its efficacy and side effects.
community The Fear of Oral Minoxidil is Overblown
Low-dose oral minoxidil is a safe and effective hair loss treatment with fewer side effects than previously feared. Users often prefer it over topical minoxidil for better results, though some experience side effects like increased body hair and cardiovascular issues.
community Anybody else obsessively searching for pp405 and counting the days?
People are eagerly awaiting the release of PP405, a new hair loss treatment. Some are using minoxidil and finasteride in the meantime, but there are concerns about scams and unverified products.
community When could we expect pp405 to hit the market?
PP405 is expected to finish Phase 2 trials in late 2025, with potential market availability around 2028-2029 if all goes well. Current treatments like finasteride and minoxidil are still popular, while new options like KX-826 and Breezula are anticipated soon.
community Can I take bicalutamide for hair loss as a man, but don’t want to transition?
A 23-year-old man with hair loss, despite using dutasteride, oral minoxidil, and RU58841, is considering bicalutamide for regrowth but is concerned about feminization. Alternatives like topical estrogen, JXL069, and spironolactone are discussed, with suggestions to explore thyroid levels and other potential underlying conditions.
Related Research
6 / 1000+ results
research Topical and oral minoxidil for hair disorders in pediatric patients: What do we know so far?
Minoxidil, applied on the skin or taken orally, can improve hair growth in kids, but more research is needed due to possible side effects.
research Efficacy and safety of oral minoxidil versus topical solution in androgenetic alopecia: a meta‐analysis of randomized clinical trials
Oral and topical minoxidil are equally effective for hair loss, but oral minoxidil causes more unwanted hair growth.
research P110 Comparative efficacy of low-dose oral minoxidil, topical minoxidil, and platelet-rich plasma with topical minoxidil in androgenetic alopecia: a randomized controlled trial
PRP with topical minoxidil is the most effective treatment for increasing hair density in androgenetic alopecia.
research 172 The impact of overlapping topical and oral minoxidil to combat temporary hair shedding during oral minoxidil initiation
Using both topical and oral minoxidil does not reduce hair shedding.
research Combating “Dread Shed”: The Impact of Overlapping Topical and Oral Minoxidil on Temporary Hair Shedding During Oral Minoxidil Initiation
Using both topical and oral minoxidil doesn't significantly reduce temporary hair shedding.
research Oral Minoxidil 5 mg versus minoxidil 5% topical solution for the treatment of male androgenetic alopecia: a double-blind randomized clinical trial.
Oral and topical minoxidil are similarly effective for hair growth, but oral may work better on the top of the head.