Is this the 2026 Hairloss Nuclear Stack? Finasteride/Dutasteride 2/21/2026
A user discusses their extensive hair loss treatment regimen, which includes dutasteride, oral and topical minoxidil, RU58841, various supplements, and lifestyle changes. The conversation includes opinions on the effectiveness and necessity of such a comprehensive approach, with some users suggesting alternatives like microneedling and questioning the high dosage of dutasteride.
View this post in the Community →
Similar Community Posts Join
5 / 1000+ resultscommunity Quote from Pelage (PP-405) Spokesperson...
Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.
community What was added to your routine that sparked the most growth?
Dutasteride, RU58841, and topical minoxidil are effective for hair regrowth, with oral minoxidil showing mixed results. Some users report significant improvement with dutasteride and topical minoxidil, while others find oral minoxidil less effective.
community Can testosterone alone cause hair loss even after nuking DHT?
Testosterone can still cause hair loss even when DHT is blocked by dutasteride, especially if hair follicles are sensitive. Topical treatments like RU58841 or pyrilutamide may help, but their long-term effectiveness is uncertain compared to dutasteride.
community Don’t Get Too Hyped About PP405. We've Seen This Movie Before.
PP405 is a new hair loss treatment showing early promise with a 20% hair density increase, but skepticism exists due to past failures of similar treatments like Pyrilutamide, RU58841, and Bimatoprost. Users debate its potential effectiveness, with some hopeful due to Google's involvement, while others urge caution without more evidence.
community Topical Minoxidil since April 2025. Finasteride since Sept 2025. Bald spot has gotten larger in area size and more noticeable in recent months. Trying to be patient but situation doesn’t seem to be resolving
The user has been using topical Minoxidil since April 2025 and Finasteride since September 2025, but their bald spot has worsened. They are considering switching to oral Minoxidil and have been advised to be patient, see a dermatologist, and possibly try additional treatments like derma rolling.
Related Research
6 / 1000+ resultsresearch Keratin 15 Promotes a Progenitor Cell State in Basal Keratinocytes of Skin Epidermis
Keratin 15 helps maintain skin cell growth and repair.
research The Integrated Stress Response Fine-Tunes Stem Cell Fate Decisions Upon Serine Deprivation and Tissue Injury
Serine is vital for hair follicle stem cells to balance hair growth and skin repair.
research Lifestyle Factors Affecting The Pathogenesis Of Androgenetic Alopecia: A Literature Review
Lifestyle changes can help manage androgenetic alopecia.
research Hoxc13 Mutant Mice Lack External Hair
Hoxc13 gene is essential for hair, nail, and papilla development.
research Miz1 Is Required for Hair Follicle Structure and Hair Morphogenesis
Miz1 is essential for proper hair structure and growth.
research Double Knockdown of the Androgen Receptor Target Genes DKK1 and SFRP1 Does Not Potentiate the Hair Growth-Promoting Effect of SFRP1 Silencing in Healthy Human Hair Follicles Ex Vivo
Silencing SFRP1 alone promotes hair growth, but adding DKK1 does not help.