Prepare to be disappointed by PP405 Research/Science 2/10/2026
Delayed release oral minoxidil is seen as a promising advancement for hair loss treatment, offering safer, higher doses and more consistent hair follicle stimulation compared to current options. However, it is not expected to replace finasteride or dutasteride, as it does not prevent androgenetic alopecia.
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6 / 1000+ resultscommunity Is that okay to start with Oral minoxidil 2.5 mg,Dutasteride 0.5mg, topical Minoxidil+Finasteride (Norwood 2 presently)
The user is considering starting oral minoxidil 2.5 mg, dutasteride 0.5 mg, and topical minoxidil+finasteride for hair loss at Norwood 2. They are also asking if they can avoid some medications and about the effectiveness of PRP with the prescribed treatments.
community Questions About Topical Finasteride & Minoxidil vs. Oral Treatment Effects and Combo Benefits
Topical finasteride with minoxidil can be effective but may not match oral finasteride results, with less absorption into the bloodstream. Shedding is common when starting or stopping minoxidil and finasteride, and adding dutasteride and tretinoin can enhance effectiveness by improving absorption and DHT inhibition.
community July 2024 to July 2025: No improvement (finasteride + dutasteride)
The user saw no hair regrowth after a year of using finasteride and dutasteride, only maintaining their current hair. Many recommend adding minoxidil for potential regrowth.
community Can Minoxidil & Finasteride Restore an M-Shaped Hairline
Minoxidil and finasteride can help regrow hair, especially in thinning areas, but restoring completely receded temples is challenging and may require a hair transplant. Some users report success with these treatments, particularly when combined with microneedling.
community Minoxidil, fin, flaking scalp, and shedding hairs
The user has been using Minoxidil and Finasteride since late 2019 with good results but is experiencing a dry, flaky scalp and shedding hairs. They also use Nizoral, biotin, zinc, magnesium, and collagen supplements, and their dermatologist prescribed fluocinolone acetonide to reduce flaking.
community Switched from FIN to DUT, hairline/temples worse
Switching from finasteride to dutasteride and oral minoxidil worsened hair thinning at the hairline and temples. The user is considering returning to finasteride, as dutasteride may not be effective for them.
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