Targeted Follicular Finasteride Delivery: A Low-Systemic Strategy Research/Science 3/28/2026
Similar Community Posts Join
5 / 141 resultscommunity UPDATE: The theory that explains everything. Please help me make this big!
Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.
community Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found
The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.
community to all people who cannot tolerate anti androgens (loe dose topical fin, pyrilutamide, CB) i am getting desperate, looking for a solution
The user tried Minoxidil without success, and Finasteride worked but caused sexual side effects even at a very low dose. They are seeking alternative treatments for hair loss as they cannot tolerate anti-androgens and are also in therapy for mental health.
community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)
There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.
community Anyone excited for CosmeRNA coming this month?
CosmeRNA, a new hair loss treatment, is expected to release soon and may become part of the "big three" treatments alongside finasteride and minoxidil. It works differently from finasteride by targeting androgen receptors in hair follicles, potentially offering fewer side effects.
Related Research
6 / 1000+ results
research Nanotechnology-Based Strategies for Hair Regeneration: Mechanistic Insights and Translational Perspectives for Androgenetic Alopecia
Nanotechnology shows promise for treating hair loss but faces safety and approval challenges.
research Active Pharmaceutical Ingredient-Ionic Liquids Assisted Follicular Co-Delivery of Ferulic Acid and Finasteride for Enhancing Targeted Anti-Alopecia
The new delivery system improves treatment for hair loss by enhancing drug absorption and effectiveness.
research A Decade of Progress in Androgenetic Alopecia Management: Emerging Therapies and Multimodal Strategies
Androgenetic alopecia treatments are becoming more personalized and include new therapies like topical antiandrogens and regenerative strategies.
research Nanotechnology-Based Strategies for Hair Follicle Regeneration in Androgenetic Alopecia
Nanotechnology shows promise for better hair loss treatments but needs more research for safety and effectiveness.
research Novel Strategies for Androgenetic Alopecia Therapy: Integrating Multifunctional Plant Extracts with Nanotechnology for Advanced Cutaneous Drug Delivery
Combining plant extracts with nanotechnology may improve hair loss treatments.
research Transfollicular Drug Delivery: Current Perspectives
Transfollicular drug delivery is promising but needs more research to improve and understand it better.