Any treatment not nuking systemic DHT levels?
    Finasteride/Dutasteride 2/21/2026

    At a glance
    In this question or advice post, the primary subjects mentioned are
    πŸ’‰ Dutasteride mesotherapy (injections)
    πŸ’§ Minoxidil (topical) 8 months
    πŸ’§ Ketoconazole (topical)
    πŸ’§ KX-826 (topical)
    πŸ’§ RU58841 (topical)
    the tone is 😐 neutral with no growth results.
    Hair loss treatments that avoid significantly lowering systemic DHT levels, focusing on topical options like dutasteride mesotherapy, minoxidil, and ketoconazole. The user is exploring alternatives like KX-826 and RU58841 due to concerns about hormone levels.
    View this post in the Community β†’

    Similar Community Posts Join

    5 / 1000+ results

      community Guys, we finally have an alternative to finasteride

      in Research/Science  263 upvotes 9 months ago
      A combination of pyrilutamide, minoxidil, and alfatradiol is proposed as an effective alternative to finasteride for treating mild to moderate hair loss, claiming to stabilize hair loss and improve thickness without finasteride's side effects. Some users are skeptical about the effectiveness and approval of these treatments, while others are interested in trying them due to finasteride's side effects.

      community 6 Month Update as a Bad Diffuse Thinner

      in Progress Pictures  58 upvotes 2 weeks ago
      A user shared their 6-month update on hair loss treatment, using daily Dutasteride, oral and topical Minoxidil, Ketoconazole shampoo, topical Finasteride, dermastamping, and PRP treatments. They reported improved hair quality but no significant regrowth or density increase, and plan to continue the regimen for another year before considering a hair transplant.

      community How to reduce scalp DHT as much as possible?

      in Finasteride/Dutasteride  16 upvotes 4 months ago
      The conversation discusses reducing scalp DHT to prevent hair loss, with a focus on using dutasteride, finasteride, and other treatments like RU58841 and minoxidil. It highlights the challenges of managing hair loss while on high testosterone levels, suggesting that dutasteride may be more effective than finasteride in such cases.

      community Homemade topical spironolactone

      in Research/Science  27 upvotes 3 years ago
      The potential effectiveness of homemade topical spironolactone in treating hair loss, with studies suggesting it is more effective than finasteride and even minoxidil when used as monotherapy. The conversation also mentions that other anti-androgens are being developed which may soon hit the market.

    Related Research

    6 / 1000+ results