21M Started young, treated early, but non-responder to dht blockers Finasteride/Dutasteride 7/4/2025
A 21-year-old male uses minoxidil, finasteride, and dutasteride for hair loss but still experiences progression with high DHT levels. Suggestions include increasing dosages, checking for deficiencies, considering a hair system, or consulting a specialist.
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5 / 1000+ resultscommunity 32, Southeast Asian, 1 y 3 m Finasteride, Dutasteride, Minoxidil, Microneedling – Former hair system user. Quick description of routine in comments.
A user named "bmbshell" who was dealing with hair loss and initially tried to fix it with a hair system before deciding to try finasteride, dutasteride, minoxidil, microneedling, and biotin supplements. They documented their progress over the past 1 year and 3 months, showing how effective these treatments were in regrowing their hair.
community Any treatment not nuking systemic DHT levels?
Hair loss treatments that avoid significantly lowering systemic DHT levels, focusing on topical options like dutasteride mesotherapy, minoxidil, and ketoconazole. The user is exploring alternatives like KX-826 and RU58841 due to concerns about hormone levels.
community How come topical finasteride even works at all?
Topical finasteride can effectively reduce scalp DHT by targeting local enzymes, despite less systemic impact compared to oral forms. Combining oral dutasteride with topical finasteride and minoxidil may enhance hair loss prevention, though evidence of its effectiveness is limited.
community Meta analysis of minoxidil only vs 5AR inhibitors
Oral dutasteride is the most effective for hair regrowth, followed by oral finasteride and minoxidil. Topical finasteride combined with minoxidil is recommended for those avoiding systemic DHT reduction.
community My story (22m, fin, min, niz, RU, dut –> part frontal hair system)
User "hairplsrn" shares their hair loss journey, trying various treatments like finasteride, minoxidil, and dutasteride, but experiencing worsening hair loss. They decide to get a partial frontal hair system and continue medication, while others offer support and advice on staying on medication and focusing on overall confidence.
Related Research
6 / 1000+ results
research Systemic treatment options for androgenic alopecia
Finasteride, dutasteride, and oral minoxidil are effective for treating hair loss, with spironolactone as an option for women.
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The new hair loss treatment combining nitric oxide and minoxidil in a special carrier is effective for hair regrowth.
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Finasteride affects the male rat brain by reducing certain protein activation, but these effects may reverse after stopping the drug.
research The shifting preferences of patients and physicians in nonsurgical hair loss treatment
Minoxidil and Finasteride are the most popular hair loss treatments, with rising interest in other options, and economic or health crises can change what treatments people prefer.
research Human Derived Immortalized Dermal Papilla Cells With a Constant Expression of Testosterone Receptor
Researchers created immortal human skin cells with constant testosterone receptor activity to study hair loss and test treatments.
research Hair loss: a clinical update
The article concludes that a thorough diagnosis and treatment plan, including medications, non-invasive methods, or surgery, is important for managing hair loss, with a combination of minoxidil and finasteride being particularly effective.