The PP405 news are the best news we've had in the last 20 or more years. Research/Science 6/17/2025
PP405 significantly improves hair density, outperforming finasteride, with 31% of users seeing over 20% improvement in four weeks. Concerns exist about its availability, cost, and long-term effects.
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6 / 445 resultscommunity Story time! The Great Unbalding (PP405)
PP405 is a promising new hair loss treatment that may reactivate dormant hair follicles without side effects. It could surpass traditional treatments like minoxidil and finasteride if successful in further trials.
community The expected timeline for PP405 - Next update at AAD Annual Meeting in March 2026 ?
A new hair loss treatment, PP405, showed promising Phase 2a results with 31% of patients experiencing over 20% hair density increase without systemic absorption, avoiding hormonal side effects. The treatment is expected to be expensive, with Phase 3 trials starting mid-2026, and there is skepticism about the data's strength.
community Anyone who started balding in their early 20s and managed to salvage their hair with fin/dut & min?
Finasteride, minoxidil, and sometimes dutasteride were used for hair loss with varying success. Some experienced side effects, while others maintained or regrew hair, considering hair transplants as a future option.
community Does finasteride works forever as long as you take it?
Finasteride can maintain hair for many years, but its effectiveness may decrease over time. Some switch to dutasteride or add minoxidil for better results, with side effects like libido changes and ED discussed.
community PP405 Might Be the Closest We Have to a Upcoming Cure
PP405 is considered a promising potential cure for hair loss, with phase 2 trial results expected in February 2025. Hair cloning is also discussed as a potential ultimate solution, despite significant scientific challenges.
community Why not just take the drugs before hair loss?
Finasteride and dutasteride are discussed as preventative treatments for hair loss, with some advocating for early use and others concerned about side effects, especially before full maturity. Many regret not starting these treatments earlier due to their effectiveness in preventing or slowing hair loss.
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