Aspects of Pathogenesis and Differentiated Approaches to Treating Skin Pathology in Women of Early Reproductive Age with Menstrual Cycle Disorders

    Vladislav Novik, Ірина Нікітіна, Світлана Герасименко, Тетяна Бабар
    The study aimed to explore the relationship between menstrual cycle disorders, hormonal profiles, and dermatological manifestations in 120 women aged 18-35. Participants were divided into three groups based on clinical and hormonal characteristics. Group I included women with menstrual disorders and signs of hyperandrogenism, such as acne and hirsutism. Group II had menstrual disorders without hyperandrogenism but with other skin issues like alopecia. The control group had regular cycles and no skin pathology. Results showed that dermatological symptoms in women with menstrual disorders are influenced by both circulating androgen levels and tissue sensitivity, as indicated by androgen receptor expression. This highlights the need for personalized treatment strategies considering hormonal and receptor profiles. The study concludes that menstrual cycle disorders are closely linked to hormone-dependent skin conditions, and a multidisciplinary approach improves diagnosis and treatment effectiveness.
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