72494 Alopecia Areata and Pregnancy: A Systematic Review and Meta-Analysis of Maternal-Fetal Outcomes

July 2026 in “ Journal of the American Academy of Dermatology ”

Lilia Maria Lima de Oliveira, Maria Luiza Rodrigues Defante, Michele Kreuz, Isabelle Albuquerque Reis, Beatriz Ximenes Mendes, Marina Mordehachvili Burlá, Lívia Maria Rosa, Fabiana Castro Porto Silva Lopes, Luiza Kalil, Christopher Bunick

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research Alopecia areata and adverse pregnancy outcomes: A systematic review and meta-analysis

September 2025 in “JAAD reviews.”

This systematic review and meta-analysis evaluated the association between alopecia areata (AA) and adverse pregnancy outcomes in women, analyzing data from 5 studies with a total of 10,611,392 patients. The findings suggest low-certainty evidence that AA may increase the risk of gestational hypertension, miscarriage, and preterm birth, with odds ratios (OR) of 1.28, 1.08, and 1.07, respectively. However, there is moderate-certainty evidence that AA is probably not associated with an increased risk of stillbirth. The study highlights the need for further high-quality research to assess the impact of AA severity and the influence of comorbid autoimmune conditions on pregnancy outcomes.

Birth Outcomes of Infants Born to Mothers with Alopecia Areata: A Nationwide Population-Based Study in Korea