77200 Infections and Therapy Lapses Predominate as Flare Triggers on Oral JAK Inhibitors for Alopecia Areata: A Retrospective Cohort Study

This retrospective cohort study investigates the triggers of flares in patients with severe alopecia areata (AA) who are treated with oral Janus kinase inhibitors (JAKis). The study identifies infections and therapy lapses as the predominant triggers for these flares. The findings highlight the importance of managing infections and ensuring adherence to therapy to maintain the effectiveness of JAKis in promoting hair regrowth in AA patients. The study provides valuable insights into the real-world application of JAKis and emphasizes the need for careful monitoring to prevent treatment interruptions and manage potential flare triggers effectively.