TLDR Combination therapy may be more effective for difficult-to-treat scalp conditions.
This case report discusses a 72-year-old male with treatment-resistant erosive pustular dermatosis of the scalp (EPDS), a rare inflammatory condition that can lead to scarring alopecia. Despite trying multiple treatments, including corticosteroids, antibiotics, calcineurin inhibitors, and isotretinoin, the patient's condition showed minimal improvement. The report suggests that combination therapy may be more effective than monotherapy for refractory EPDS. The case highlights the challenges in diagnosing and managing EPDS, emphasizing the importance of considering combination therapies and the potential need for biopsy in non-responsive cases.
13 citations
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June 2020 in “International Journal of Dermatology” A rare scalp condition mainly in older women can be treated with various alternatives to steroids, which may have fewer side effects.
13 citations
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September 2019 in “Clinical, Cosmetic and Investigational Dermatology” Early treatment of EPDS can improve outcomes and reduce recurrence risk.
8 citations
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April 2019 in “Australasian Journal of Dermatology” The article suggests a treatment plan for a stubborn scalp condition common in elderly Australians to help improve their lives.
16 citations
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October 2013 in “Anais Brasileiros de Dermatologia” Scalp condition healed with prednisone and tacrolimus.
5 citations
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October 2018 in “Burns” Most patients who had scalp skin removed for burns as children had normal hair growth and were satisfied years later.
4 citations
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July 2015 in “Case Reports in Dermatology” A woman with unexplained hair loss was found to have harmless skin tumors and a scarring hair loss condition, but the tumors didn't cause the hair loss.