Update to Acne Vulgaris Treatment for Canadian Practice
July 2025
in “
Canadian Family Physician
”
TLDR Use topical treatments for mild acne and oral treatments for moderate to severe acne, avoiding antibiotic monotherapy.
The 2024 American Academy of Dermatology guidelines for managing acne vulgaris in Canada emphasize evidence-based practices, recommending topical therapies like benzoyl peroxide and antibiotics, with retinoids and clascoterone receiving conditional recommendations. Oral treatments such as doxycycline and isotretinoin are strongly endorsed, with isotretinoin being the standard for severe acne. Antibiotic monotherapy is discouraged to prevent resistance, advocating for combination treatments. New topical treatments like trifarotene and clascoterone show excellent efficacy and safety. Special considerations are advised for pregnant individuals, those with skin of color, and transgender individuals, highlighting specific risks and treatment adaptations.
