Acquired Ichthyosis, Alopecia, and Loss of Hair Pigment Associated with Leiomyosarcoma

    March 1998 in “ JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology ”
    A Farrell
    TLDR Removing a tumor may resolve associated skin and hair symptoms.
    The document reports the case of a 70-year-old woman with acquired ichthyosis and leiomyosarcoma, a less common malignancy associated with this condition. She also exhibited unusual symptoms of generalized thinning and loss of hair pigment. A scalp biopsy confirmed the presence of ichthyosis. After the tumor was surgically removed, the ichthyosis resolved, and her hair began to regrow with darker pigment. This case highlights the potential association between acquired ichthyosis and internal malignancies, and the possible resolution of symptoms following successful treatment of the underlying malignancy.
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