Effects of Adrenocorticotropic Hormone on Body Growth, Visceral Proportions, and White Blood Cell Counts of Normal and Hypophysectomized Male Rats

May 1951 in “ Endocrinology ”

C. Willet Asling, W. O. Reinhardt, Choh Hao Li

adrenocorticotropic hormone pituitary growth hormone somatic growth hair growth

TLDR Adrenocorticotropic hormone inhibits growth and affects body composition in male rats.

The study aimed to induce growth stasis in male rats through adrenocorticotropic hormone injections, observing effects on body growth, visceral proportions, and white blood cell counts. The research builds on previous findings that this hormone inhibits somatic growth and affects hair growth and visceral weight. The study confirms the hormone's antagonistic effects on pituitary growth hormone, with further details on skeletal changes and body composition to be explored in future papers.

View this study on doi.org →

Discuss this study in the Community →

Similar Research

5 / 794 results

research Recent Advances in the Molecular Mechanisms Causing Primary Generalized Glucocorticoid Resistance

15 citations , April 2016 in “Hormones”

Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.

research Neuroendocrinology of Epithelial Hair Follicle Stem Cells

42 citations , March 2008 in “Molecular and Cellular Endocrinology”

Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.

Deciphering the Function of Canonical Wnt Signals in Development and Disease: Conditional Loss- and Gain-of-Function Mutations of β-Catenin in Mice

research Deciphering the Function of Canonical Wnt Signals in Development and Disease: Conditional Loss- and Gain-of-Function Mutations of β-Catenin in Mice

556 citations , September 2008 in “Genes & Development”

Wnt signaling is vital for cell growth, development, and cancer research.

research Potential Factors Contributing to Androgenetic Alopecia

8 citations , January 1996 in “Springer eBooks”

Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.

research Steroidogenic Factor-1 Lineage Origin of Skin Lesions in Carney Complex Syndrome

3 citations , May 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

Skin lesions in Carney Complex are caused by a gene change in some skin cells that leads to increased pigmentation and may lead to tumors.