TLDR Adipose-derived stem cells are promising for tissue and organ repair due to their easy access and versatility.
The document reviewed the potential of adipose-derived stem cells (ASCs) in tissue engineering and regenerative medicine, emphasizing their accessibility and ability to differentiate into various cell types. ASCs were explored for applications in treating diseases like diabetes and multiple sclerosis, with 3D scaffolds enhancing their proliferation and differentiation. The review highlighted the importance of scaffold design, external stimuli, and growth factors in optimizing ASC applications. Despite promising results in laboratory studies and some clinical cases, challenges such as understanding ASC interactions, ensuring long-term safety, and limited clinical trials remained. The document concluded that further research and clinical trials were necessary to address these issues and fully realize the potential of ASCs in regenerative therapies.
41 citations
,
July 2012 in “Stem Cells and Development” Low-dose UVB light improves hair growth effects of certain stem cells by increasing reactive oxygen species.
47 citations
,
July 2013 in “Pharmacological Reviews” Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.
70 citations
,
August 2020 in “Nanomaterials” Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.
43 citations
,
July 2019 in “Stem Cells International” Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.
3 citations
,
April 2022 in “Bioengineering” Ultrasound can help deliver genes to cells to stimulate tissue regeneration and enhance hair growth, but more research is needed to perfect the method.
57 citations
,
March 2018 in “International Journal of Molecular Sciences” The extracellular matrix is crucial for controlling skin stem cell behavior and health.
113 citations
,
November 2017 in “Scientific Reports” Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.