Composition, Isolation, Identification, and Function of Adipose Tissue-Derived Exosomes

The document reviewed the composition, isolation, identification, and function of adipose tissue-derived exosomes (AT-Exosomes), which are nano-sized extracellular vesicles involved in cell communication. It highlighted the role of AT-Exosomes in regulating metabolic homeostasis in organs like the liver and skeletal muscle and their potential involvement in disease treatment and progression. The review detailed methods for isolating and identifying exosomes, categorized relevant studies, and summarized the components and functions of mammalian exosomes. It also discussed the crosstalk of AT-Exosomes within adipose tissue and their impact on other tissues, while identifying unresolved issues and future research directions.