Adolescent Acne: Association to Sex, Puberty, Testosterone and Dihydrotestosterone

    March 2025 in “ Endocrine Connections ”
    Nanna E. Jakobsen, Jørgen Holm Petersen, Lise Aksglæde, Casper P. Hagen, Alexander S. Busch, Trine Holm Johannsen, Hanne Frederiksen, Anders Juul, Stine Agergaard Holmboe
    TLDR Higher DHT levels are linked to more acne in adolescents, especially boys.
    The study investigated the prevalence of acne in adolescents and its association with sex, puberty, and androgen levels, using data from 1,609 participants aged 5.6-23.4 years. Acne was more prevalent in late pubertal boys (85%) compared to girls (15%), with boys experiencing acne at a mean age of 15 years. Higher concentrations of dihydrotestosterone (DHT) were found in adolescents with acne, indicating a link between elevated DHT levels and acne presence. The study highlights the significant role of androgens, particularly DHT, in the development of acne during puberty.
    Discuss this study in the Community →

    Research cited in this study

    2 / 2 results

    Related Community Posts Join

    6 / 938 results
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      by nkrata in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Does finasteride/dutasteride reverse aging?

      in Chat  45 upvotes 1 year ago
      Finasteride and dutasteride can improve skin texture and reduce acne by lowering DHT but do not reverse aging. They may enhance skin and hair health for some, but can also cause side effects like dry skin and sexual dysfunction.
      Can I still save my hairline at age of 15?

      community Can I still save my hairline at age of 15?

      by Kuba in General  532 upvotes 4 months ago
      A 15-year-old is concerned about hair loss, possibly at Norwood 2 or 3, and is using shampoos and conditioners recommended by a trichologist. Suggestions include considering topical minoxidil and consulting a doctor about topical anti-DHT treatments like finasteride or RU58841, but avoiding 5-alpha-reductase inhibitors at this age.

      community Why is dht bad for scalp hair but good for hair on the rest of body?

      in Satire  109 upvotes 2 years ago
      The conversation discusses why DHT (dihydrotestosterone) negatively affects scalp hair but promotes growth elsewhere on the body. Various opinions include genetic predispositions, differences in hair follicle reactions to DHT, and the potential role of Omega-3 in reducing inflammation and promoting hair health.

    Related Research

    1 / 1 results