Recent Advances in 3D Bioprinting of Tissues and Organs for Transplantation and Drug Screening

    August 2024 in “ Virtual and Physical Prototyping
    Xuming Sun, Wu Ren, Linyan Xie, Qiongqiong Ren, Zhaoju Zhu, Qianfang Jia, Wenshuai Jiang, Zhen Jin, Yi Yu
    TLDR 3D bioprinting could solve organ shortages and improve drug testing.
    This review discusses the potential of 3D bioprinting as a solution to the challenges of organ transplantation and drug testing, particularly addressing the shortage of organ donors and the limitations of 2D cell cultures and animal models. It outlines various bioprinting technologies, such as jetting-based, extrusion-based, and vat photopolymerization-based methods, as well as emerging approaches. The review also covers different bioinks, cell sources, and recent applications of 3D bioprinted tissues and organs. It concludes by examining the challenges and future prospects of 3D bioprinting in the context of transplantation and drug screening, aiming to advance the field towards practical implementation.
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