Analysis of Common Treatment Drugs and Allergen Sensitization in Hair Loss Patients

The study examined allergen sensitization in 196 hair loss patients through patch tests, focusing on common hair loss types and treatment drugs. Results indicated that 7 cosmetic ingredients, including preservatives and metals, were prone to sensitization. Notably, dodecyl polyglucoside had a 10.20% positivity rate, while metal allergens cobalt chloride and nickel sulfate had rates of 56.63% and 32.65%. Topical medications like ketoconazole lotion showed a 50.00% positivity rate. Minoxidil formulations had significant sensitization potential, with rates decreasing when combined with hydrocortisone. The study underscores the importance of patch testing to minimize allergic reactions and improve treatment compliance, advocating for personalized treatment approaches. Limitations include potential errors from varying concentrations, suggesting a need for larger-scale studies.