Regenerative Potential of Allogeneic Adipose Tissue-Derived Mesenchymal Cells in Canine Cutaneous Wounds

The study investigated the use of allogeneic adipose-derived mesenchymal stem cells (ASCs) for treating cutaneous wounds in a 2-year-old dog. The ASC treatment led to faster wound healing and re-epithelialization compared to conventional methods, with complete closure and hair regrowth by day 25. Histopathological analysis showed reduced inflammation and the presence of hair follicles in the treated areas. Additionally, ASCs exhibited immunomodulatory effects by inhibiting T lymphocyte proliferation, suggesting safety and no risk of graft rejection. However, the study's findings were based on a single case, highlighting the need for further research to validate these results.