Alopecia Areata in Atopic Dermatitis: Coincidence or Regularity?

    January 2022 in “ Russian Medical Inquiry ”
    S.Yu. Petrova, V.I. Albanova
    TLDR Atopic dermatitis may trigger alopecia areata, and early treatment can help prevent severe cases.
    The document reviewed the association between atopic dermatitis (AD) and alopecia areata (AA), suggesting that AD might contribute to AA development through immune system interactions, particularly involving Treg, Th17, and Th1 lymphocytes. It found that a hyperactive Th2 response could worsen AA in AD patients, and treatments blocking IL-4, IL-13, and histamine receptors showed promise in regressing baldness. The study emphasized the importance of treating both skin and hair in AD patients to mitigate autoimmune risks and highlighted the potential for severe combined manifestations in genetically predisposed offspring. Despite these findings, the study's small sample size limited its reliability, underscoring the need for further research.
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