Alopecia Areata: Mechanisms, Targeted Therapies, And Translational Challenges
May 2026
in “
Current Opinion in Pharmacology
”
Research cited in this study
34 / 34 resultsresearch Is Spontaneous Regrowth in Alopecia Areata Possible: A Systematic Review and Meta-Analysis of Placebo-Controlled Studies
Spontaneous hair regrowth in alopecia areata is possible but varies greatly among individuals.
research Alopecia Areata: A Comprehensive Review of Clinical, Immunologic, and Genetic Perspectives
Alopecia Areata is an autoimmune disease causing hair loss, with no cure yet, but research may lead to new treatments.
research Overlapping Features of Atopic Dermatitis and Alopecia Areata: From Pathogenesis to Treatment
Atopic dermatitis and alopecia areata share immune and genetic factors, and targeted therapies may help both.
research Treatment Outcomes and Considerations for Topical Immunotherapy in Patients with Alopecia Totalis and Alopecia Universalis
Topical immunotherapy can help with severe hair loss, but results vary and need personalized, long-term treatment.
research Pathophysiology of Alopecia Areata in the Pediatric Patient
Alopecia areata in children is caused by the immune system attacking hair follicles due to genetic factors.
research Systemic Therapies for Pediatric Alopecia Areata
Janus kinase inhibitors are the most supported treatment for pediatric alopecia areata, while other options have limited evidence.
research Upadacitinib for Alopecia: Current Evidence and Clinical Insights
Upadacitinib helps most people with alopecia regrow hair quickly and is generally safe.
research Alopecia Areata Treated Using CO2 Fractional Laser With Different Parameters
CO2 fractional laser treatment helped regrow hair in a 13-year-old with alopecia areata.
research Identifying Effective Immune Biomarkers in Alopecia Areata Diagnosis Based on Machine Learning Methods
Machine learning can help find new ways to treat alopecia areata.
research Alopecia Areata Treatment: Past, Present, And Future
New treatments for Alopecia Areata, like JAK inhibitors, are effective, and future research is exploring advanced therapies.
research Light-Based Therapies in the Treatment of Alopecia
Light-based therapies show promise as safe treatments for hair loss.
research A Phase 2a Trial of Brepocitinib for Cicatricial Alopecia
Brepocitinib effectively reduces inflammation and improves symptoms in cicatricial alopecia with good safety.
research Mesenchymal Stem Cell Therapy in Alopecia Areata: Visual and Molecular Evidence from a Mouse Model
Mesenchymal Stem Cell therapy shows promise for treating hair loss in Alopecia Areata.
research Lifetime Incidence and Healthcare Disparities in Alopecia Areata: A UK Population-Based Cohort Study
Alopecia areata affects 1 in 50 people, with non-White ethnic groups experiencing the most impact on mental health and work.
research Efficacy and Safety of Deuruxolitinib, an Oral Selective Janus Kinase Inhibitor, in Adults with Alopecia Areata: Results from the Phase 3 Randomized, Controlled Trial (THRIVE-AA1)
Deuruxolitinib effectively promotes hair regrowth in adults with alopecia areata.
research Progress of Clinical Research on Fractional Laser Treatment of Androgenetic Alopecia: A Review Article
Fractional laser therapy is a promising, effective, and minimally invasive treatment for hair loss.
research Delivery Strategies of siRNA Therapeutics for Hair Loss Therapy
Effective delivery systems are crucial for siRNA hair loss treatments to work better.
research Deciphering the Complex Immunopathogenesis of Alopecia Areata
Alopecia areata is caused by immune attacks on hair follicles, affecting hair growth and quality of life.
research Gut Microbiome, Metabolome and Alopecia Areata
The health of the gut may be important in developing new ways to prevent, diagnose, and treat alopecia areata.
research Inhibition of T-Cell Activity in Alopecia Areata: Recent Developments and New Directions
New treatments targeting T-cell pathways are needed for better alopecia areata management.
research Gene Therapy for Alopecia in Type II Rickets Model Rats Using Vitamin D Receptor-Expressing Adenovirus Vector
Gene therapy helped rats with a specific type of rickets grow hair without severe inflammation.
research Ritlecitinib: First Approval
Ritlecitinib is approved in the USA and Japan for treating severe hair loss in people aged 12 and older.
research Clinical Outcomes for Uptitration of Baricitinib Therapy in Patients With Severe Alopecia Areata
Increasing the dose of baricitinib to 4 mg helps more patients with severe alopecia areata regrow hair.
research Efficacy and Safety of Ritlecitinib in Adolescents with Alopecia Areata: Results from the ALLEGRO Phase 2b/3 Randomized, Double-Blind, Placebo-Controlled Trial
research Effective Treatment of Refractory Alopecia Areata in Pediatric Patients With Oral Abrocitinib
A new drug, abrocitinib, helped a child with severe hair loss regrow hair.
research Janus Kinase Inhibitors for Alopecia Areata: A Narrative Review
Janus kinase inhibitors can regrow hair in alopecia areata but may cause side effects and hair loss may return if treatment stops.
research Biomarkers in Alopecia Areata: A Systematic Review and Meta-Analysis
High levels of IL6 and CRP, and low levels of vitamin D, might be indicators of alopecia areata.
research Autoantigen Discovery in the Hair Loss Disorder, Alopecia Areata: Implications of Post-Translational Modifications
New protein changes may be involved in the immune attack on hair follicles in alopecia areata.
research Hair Follicle-Derived Mesenchymal Stem Cells Decrease Alopecia Areata Mouse Hair Loss and Reduce Inflammation Around the Hair Follicle
Hair follicle stem cells reduced hair loss and inflammation in mice with a condition similar to human alopecia.
research Alopecia Areata: An Update on Etiopathogenesis, Diagnosis, and Management
JAK inhibitors show promise for treating alopecia areata, but more research is needed.
research The Alopecia Areata Investigator Global Assessment Scale: A Measure for Evaluating Clinically Meaningful Success in Clinical Trials
The AA-IGA scale reliably measures treatment success in alopecia areata by considering both clinician and patient views.
research Efficacy of Fractional Lasers in Treating Alopecia: A Literature Review
Fractional lasers seem effective and safe for treating hair loss, but more research is needed to find the best treatment methods.
research A Review on Laser and Light-Based Therapies for Alopecia Areata
Laser and light therapies, especially the 308 nm excimer laser, are effective and safe for treating alopecia areata, but more research is needed.
research Trichohyalin Is a Potential Major Autoantigen in Human Alopecia Areata
Trichohyalin may trigger the immune response causing alopecia areata.