TLDR An HIV patient's complete hair loss was reversed after switching from lopinavir/ritonavir to nelfinavir.
A 62-year-old HIV patient experienced alopecia totalis of the scalp, eyebrows, and eyelashes 18 months after starting antiretroviral therapy with lopinavir/ritonavir, efavirenz, and stavudine. The alopecia reversed completely within 2 months after substituting nelfinavir for lopinavir/ritonavir, with no other changes in treatment. This case was notable as it was the second reported instance of lopinavir/ritonavir-associated alopecia totalis in the international literature.
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July 2003 in “Journal of the American Academy of Dermatology” Clobetasol propionate ointment can help some people with total hair loss regrow hair.
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February 2018 in “Journal of Investigative Dermatology” Tofacitinib may help treat severe hair loss, but more research is needed.
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March 2023 in “JAMA Dermatology” Alopecia areata and its severe forms are becoming more common, especially among females, adults, and people in the Northeast.
