Alopecia Associated With the Use of Disease-Modifying Therapies for Multiple Sclerosis: A Scoping Review Protocol
January 2026
in “
Open Science Framework
”
TLDR Some treatments for multiple sclerosis can cause hair loss.
This scoping review protocol aims to systematically map the literature on alopecia associated with disease-modifying therapies (DMTs) for multiple sclerosis (MS), particularly focusing on immune reconstitution therapies like alemtuzumab. It will explore the types, mechanisms, and incidence patterns of alopecia linked to these treatments, addressing gaps in knowledge and proposing recommendations for clinicians. The review will include data from clinical trials and pharmacovigilance reports, providing a narrative synthesis of findings without statistical analyses. The conclusions will be based on methodological criteria, and the results will be disseminated through a peer-reviewed journal and conferences.