Alopecia Neoplastica Due to Gastric Adenocarcinoma Metastasis to the Scalp, Presenting as Alopecia: A Case Report and Literature Review

Alopecia neoplastica is a rare form of hair loss caused by the metastasis of visceral malignancies, such as gastric adenocarcinoma, to the scalp. This case report detailed a 33-year-old woman who developed alopecia neoplastica while undergoing chemotherapy for gastric adenocarcinoma. The condition was characterized by metastatic adenocarcinoma cells found in the scalp biopsy, which were confirmed to originate from the primary gastric tumor through immunohistochemical analysis. The study highlighted the role of tumor invasion in causing hair follicle atrophy, contributing to the development of alopecia neoplastica, and provided insights into its pathogenesis.