Alopecia Totalis: Significant Hair Regrowth with Fluocinolone Acetonide Cream

A 34-year-old woman with alopecia totalis of 5 years duration experienced significant hair regrowth after being treated with 0.025% fluocinolone acetonide cream under an occlusive plastic dressing. The treatment involved applying the cream and covering it with a plastic film for 48 hours every 72 hours. After 3.5 months, her hair grew to 3 cm, and by September 1962, it reached 5 cm with normal texture and color. The patient showed no systemic side effects, and the treatment's success suggests that the corticosteroid acts locally, possibly facilitated by the occlusive dressing.