ALX4-Related Frontonasal Dysplasia Sequence Presenting With Alopecia in a 12-Year-Old Girl

December 2023 in “ The Sri Lanka Journal of Dermatology ”

K.L.P.D. Seneviwickrama, S. K. P. Lekamge, H. M. P. Gunathilake

alopecia ALX4-related frontonasal dysplasia FND alopecia areata telogen effluvium genetic syndromes hair loss ALX4-related FND

TLDR A 12-year-old girl's hair loss was linked to a rare genetic condition called ALX4-related frontonasal dysplasia.

This case report describes a 12-year-old girl presenting with alopecia as part of the ALX4-related frontonasal dysplasia (FND) sequence, a rare condition. The report highlights the importance of considering genetic causes like ALX4 mutations in pediatric patients with alopecia, beyond more common conditions such as alopecia areata and telogen effluvium.

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