Androgen Excess Disorders Remain Undiagnosed in One of Every Four Premenopausal Women With Type 1 Diabetes

    January 2025 in “ Human Reproduction Open ”
    A. Bayona Cebada, Lía Nattero‐Chávez, Esther de la Calle de la Villa, Alejandra Quintero Tobar, Sara de Lope Quiñones, Beatriz Dorado Avendaño, Tom Fiers, Kaufman Jean-Marc, Manuel Luque‐Ramírez, Héctor F. Escobar‐Morreale
    TLDR 25% of premenopausal women with Type 1 diabetes have undiagnosed androgen excess disorders.
    The study reveals that 25% of premenopausal women with Type 1 diabetes (T1D) have undiagnosed androgen excess disorders, such as polycystic ovary syndrome (PCOS). Conducted on 149 women with T1D, the research found that these women often exhibit milder hyperandrogenic symptoms and lower free testosterone levels compared to typical PCOS patients. The study emphasizes the need for routine screening, particularly for those diagnosed with T1D before menarche, to prevent negative health impacts. Despite potential selection bias and the limitations of its cross-sectional design, the study underscores the importance of recognizing and diagnosing these disorders to improve health outcomes for women with T1D.
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