TLDR Testosterone in older women can increase bone density, muscle mass, fat mass, improve memory, and boost libido, but may cause nipple color changes.
The 2018 document discussed the impact of androgens, specifically testosterone, on postmenopausal women's health. It was found that higher levels of free testosterone in older women were linked to increased bone mineral density, lean body mass, and total fat mass. Additionally, testosterone improved verbal learning and memory in postmenopausal women not on estrogen therapy. The document also explored the use of testosterone in treating hypoactive sexual desire disorder in postmenopausal women, showing its effectiveness in enhancing libido. However, potential side effects like nipple and areolar hyperpigmentation due to the use of estradiol spray were also mentioned.
75 citations
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February 2016 in “The Journal of Sexual Medicine” Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.
251 citations
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October 2014 in “The Journal of Clinical Endocrinology & Metabolism” The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.
18 citations
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May 2014 in “Menopause” A 5 mg dose of transdermal testosterone cream effectively restores testosterone levels in postmenopausal women.
21 citations
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December 2012 in “Maturitas” Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.
53 citations
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January 2006 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Reduced AR gene methylation may cause early pubic hair growth in girls.
