Anthropometric Characteristics of Polycystic Ovary Syndrome and Their Associations with Insulin Resistance and Lipid Profile

This study, involving 126 women with PCOS and 159 controls, found that women with PCOS had higher body mass index, fat mass percentage, and insulin resistance (HOMA-IR) compared to controls. Increased fat mass was linked to higher triglycerides and LDL cholesterol, and lower HDL cholesterol, regardless of PCOS status. Lean mass was associated with a better metabolic profile. The study concluded that body composition, particularly fat mass, was a predictive factor for lipid metabolism alterations, and PCOS was independently associated with worse insulin resistance. These findings emphasized the importance of early diagnosis and lifestyle interventions to manage PCOS-related metabolic disturbances.