Antiproliferative and Antioxidant Potential of Tridax Procumbens Extracts Against Various Human Cancer Cell Lines: An Insight for Medicines From Weeds

This study investigates the anticancer and antioxidant properties of Tridax procumbens extracts, revealing their potential in cancer treatment. The extracts were tested on various human cancer cell lines, showing inhibitory effects with IC 50 values ranging from 23.41 to 90.76 g/mL. Notably, the chloroform fraction of the stem exhibited strong activity against A431 and MDA-MB-231 cell lines. Antioxidant activity was also significant, with IC 50 values between 14.70 and 93.80 g/mL, particularly in the DPPH and nitric oxide assays. HPLC analysis identified high levels of ferulic acid and kaempferol in the flower part, contributing to the strong antioxidant and antiproliferative effects observed. This research underscores the potential of Tridax procumbens as a source of plant-based compounds for cancer therapy.