Evaluation of Antihistaminic Activity in Moringa Oleifera Seeds: A Phytochemical and Pharmacological Investigation

The study investigates the antihistaminic and antihelminthic activity of methanolic extract from Moringa oleifera seeds. Moringa oleifera, a plant known for its muscle relaxant properties, was evaluated for its potential to act as an antihelminthic agent, offering a safer alternative to standard drugs like albendazole, which have side effects such as nausea and temporary hair loss. Phytochemical analysis revealed the presence of alkaloids, glycosides, flavonoids, steroids, carbohydrates, and tannins. The antihelminthic activity was tested using Indian adult earthworms (Pheretima posthuma), with results measured by the time taken for paralysis and death of the worms. The study suggests that Moringa oleifera could be a viable herbal alternative with fewer side effects.