Antioxidant Natural Plant Constituents For Diabetic Wound Repair

Diabetic wound healing is hindered by oxidative stress, bacterial infections, and chronic inflammation. Antioxidant compounds from natural plants are being researched for their potential to improve diabetic wound healing. These compounds help by scavenging reactive oxygen species, reducing oxidative stress, controlling bacterial infections, and inhibiting pro-inflammatory cytokines. They also enhance antioxidant enzyme activity, promoting fibroblast and keratinocyte proliferation and migration, which aids tissue regeneration. The paper discusses the role of these plant-based antioxidants in modulating oxidative stress, managing infections, influencing inflammation, and promoting wound repair, along with their delivery systems, clinical applications, and future research directions.