TLDR Antler stem cell exosomes improve wound healing and reduce scarring.
The study explores the use of antler stem cell-derived exosomes (AnSC-exos) in promoting regenerative wound healing in a rat model. AnSC-exos significantly accelerated wound healing and improved the quality of healing by enhancing the regeneration of hair follicles, sebaceous glands, and collagen structure. They effectively inhibited the fibroblast-to-myofibroblast transition (FMT), a key process in scarring, by down-regulating the TGF-β1 pathway. AnSC-exos were as effective as antler stem cells and more potent than bone marrow mesenchymal stem cell-derived exosomes, suggesting their potential as a novel, cell-free therapeutic for scarless wound healing.
74 citations
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June 2021 in “Frontiers in Cell and Developmental Biology” Human amniotic fluid stem cell-derived exosomes improve wound healing and reduce scarring.
1036 citations
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August 2019 in “Cells” Mesenchymal stem cells can help repair body tissues with low risk of rejection.
176 citations
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June 2019 in “Cells” Different fibroblasts play key roles in skin healing and scarring.
145 citations
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November 2018 in “Nature Communications” The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.
232 citations
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October 2015 in “International journal of molecular sciences” Stem cells are crucial for skin repair and new treatments for chronic wounds.
518 citations
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November 2014 in “Science” Skin grafting and wound treatment have improved, but we need more research to better understand wound healing and create more effective treatments.
139 citations
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May 2020 in “Stem Cell Research & Therapy” Exosomes from stem cells help wounds heal faster by affecting specific cell signals.
74 citations
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June 2021 in “Frontiers in Cell and Developmental Biology” Human amniotic fluid stem cell-derived exosomes improve wound healing and reduce scarring.
9 citations
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January 2018 in “Stem Cells International” Deer antler stem cell fluid helps regenerate tissue better than fat-derived stem cell fluid.
1 citations
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October 2023 in “Journal of plastic, reconstructive & aesthetic surgery” Stem cell-derived conditioned medium is effective in improving hair density and thickness for alopecia treatment.
26 citations
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July 2021 in “Frontiers in Cell and Developmental Biology” The review suggests that a special cell-derived treatment shows promise for various skin conditions and hair growth but needs more research for confirmation.
