Arachis Hypogaea L. Root Extract Mitigates Testosterone Propionate-Induced Benign Prostatic Hyperplasia in ICR Mice by Suppressing Inflammation, Androgen Receptors, and Dihydrotestosterone

    March 2026 in “ Food Science & Nutrition
    Samee‐Ullah, Faryal Shaukat, Muhammad Umair Ijaz, Muhammad Bilal, Anees Ahmed Khalil, Tausif Ahmad, Yemin Guo, Xia Sun, Yuanda Song, Mohammed Mansour Quradha
    TLDR Arachis hypogaea L. root extract reduces prostate enlargement and inflammation in mice.
    The study investigates the effects of Arachis hypogaea L. root extract on testosterone propionate-induced benign prostatic hyperplasia (BPH) in ICR mice. The findings suggest that the root extract effectively mitigates BPH by suppressing inflammation, androgen receptors, and dihydrotestosterone levels. This indicates a potential therapeutic role for Arachis hypogaea L. root extract in managing BPH, highlighting its anti-inflammatory and anti-androgenic properties. The study provides a basis for further research into its application for BPH treatment.
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