Asl us soos [Glycyrrhiza glabra (Linn)]: An evidence-based review on its phytopharmacological, therapeutic potential and gastrodudenal ulcer activity

Glycyrrhiza glabra, commonly known as licorice, has demonstrated significant potential in treating gastroduodenal ulcers due to its phytochemical components like glycyrrhizin, tannins, and flavonoids. These compounds exhibit strong antioxidant, anti-inflammatory, and cytoprotective properties, making the hydroalcoholic extract of G. glabra effective in reducing stomach acid, enhancing mucosal defenses, and suppressing Helicobacter pylori colonization. The extract's antiulcer activity is comparable to or better than standard drugs such as omeprazole and cimetidine. Despite its traditional use and promising results, further systematic and clinical research is needed to optimize extract formulations and ensure long-term safety.