Association of Atopic Dermatitis with Metabolic Syndrome

The literature review by Alexander Gekhman explores the association between atopic dermatitis (AD) and metabolic syndrome (MetS), analyzing 11 studies. The review finds a consistent link between AD and obesity, especially in moderate-to-severe cases, suggesting the need for targeted metabolic screening in these patients. However, the associations with other MetS components such as dyslipidemia, hypertension, and hyperglycemia are inconsistent, indicating a need for further research. The study also highlights the influence of gender, ethnicity, and AD severity on MetS components, particularly obesity and hypertriglyceridemia. Both AD and MetS share a common pathophysiological pathway involving chronic inflammation and cytokines, which could be targeted in future treatments.