The Use of Avian Yolk Antibodies in Biomedical Research
September 2023
in “
Laboratornye Zhivotnye dlya nauchnych issledovanii (Laboratory Animals for Science)
”
TLDR Avian yolk antibodies offer a promising, ethical alternative for disease prevention and therapy.
The document explores the use of avian yolk antibodies (IgY) in biomedical research, emphasizing their advantages over mammalian antibodies, such as non-invasive extraction and the ability to produce large quantities without side effects. IgY has shown potential in diagnostics, therapy, and disease prevention, with applications in treating dental caries, gastric ulcers, celiac disease, Ebola, COVID-19, and venom neutralization. Notably, ostrich IgY antibodies demonstrated greater efficacy in treating androgenetic alopecia than traditional treatments. The review highlights the versatility and cost-effectiveness of IgY technology, which has matured significantly over the past two decades, offering promising alternatives for passive immunization and therapeutic applications.