Effectiveness of Baricitinib for Nasal, Genital, and Beard Hair Regrowth in Patients with Severe Alopecia Areata: 12-Month Outcomes from a Prospective Observational Study

    November 2025 in “ SKIN The Journal of Cutaneous Medicine ”
    Justin Ko, Karan Lal, Michelle Tarbox, Susan Ball, Angelina Sontag, Firas Dabbous, Mary Kate Ladd, Klaudia Kornalska, Najwa Somani, Jerry Shapiro
    Image of study
    TLDR Baricitinib significantly regrows hair in nasal, genital, and beard areas for severe alopecia areata.
    A 12-month study with 254 adults with severe alopecia areata found that baricitinib, a JAK inhibitor, led to significant hair regrowth in nasal (52%), genital (44%), and beard areas (53%). Participants also reported reduced bothersomeness of hair loss, initially rated high. These results suggest baricitinib's potential for treating hair loss beyond the scalp, offering a holistic approach for severe AA.
    Discuss this study in the Community →