Baricitinib Induced Hypoglycemic Seizures in a Patient with Hair Loss and Type I Diabetes Mellitus: A Case Report

A case report discusses a 60-year-old female with alopecia areata and type 1 diabetes mellitus who experienced hypoglycemic seizures after starting baricitinib, a JAK1/JAK2 inhibitor used for hair regrowth. Despite the seizures, the patient preferred to continue the medication due to its positive effects on her hair, leading to a dose reduction from 4mg to 2mg daily, which resolved the seizures and stabilized glucose levels. Although hypoglycemia is not a known side effect of baricitinib, the case suggests a potential link between JAK inhibitors and hypoglycemia in at-risk patients, highlighting the need for careful glucose monitoring and patient education as the use of JAK inhibitors in dermatology increases.