Bioactive Compounds In Neurocosmetics: Bridging Nature-Derived Peptides And Synthetic Molecules For Advanced Skin Health And Well-Being

The review explores the field of neurocosmetics, focusing on bioactive compounds like nature-derived peptides and synthetic molecules that improve skin health and emotional well-being by leveraging the skin-brain axis. It highlights the efficacy of compounds such as Poretect and Neurophroline in reducing inflammation and enhancing skin barrier function, and synthetic peptides like Acetyl Hexapeptide-3 in reducing wrinkles and melanin. Advanced delivery systems, including nanoencapsulation and microneedles, are discussed for overcoming skin permeability challenges. The review also addresses regulatory considerations and identifies knowledge gaps in long-term efficacy and personalized approaches.