Bioactive Compounds In Neurocosmetics: Bridging Nature-Derived Peptides And Synthetic Molecules For Advanced Skin Health And Well-Being

The review discusses the field of neurocosmetics, which uses bioactive compounds, including natural peptides and synthetic molecules, to improve skin health and emotional well-being via the skin-brain axis. It highlights the effectiveness of compounds like Acetyl Hexapeptide-3 in reducing wrinkles and Neurophroline™ in decreasing inflammation. Advanced delivery systems, such as nanoencapsulation, are noted for enhancing bioavailability, though challenges with permeability persist. The review underscores the need for long-term efficacy studies, personalized approaches, and harmonized global regulations to ensure safety and innovation. The future of neurocosmetics may involve combining natural compounds' multifunctionality with synthetic molecules' precision, offering holistic treatments for stress-related skin conditions.