Bioactive Phytoconstituents for Hair Growth: Signaling Pathways and Emerging Delivery Systems

This review highlights the potential of plant-derived bioactive compounds as alternative treatments for alopecia, addressing the limitations of current therapies like minoxidil and finasteride. It examines 18 medicinal plants traditionally used for hair restoration, focusing on their pharmacological mechanisms and key phytoconstituents. The review also discusses experimental and clinical evidence supporting their efficacy. Additionally, it explores emerging trends in alopecia management, such as nanotechnology, stem cell therapy, and gene modulation, suggesting these could enhance the integration of phytochemicals into clinical practice for hair growth promotion.