Bioactive Phytoconstituents for Hair Growth: Signaling Pathways and Emerging Delivery Systems

Alopecia, or hair loss, is a widespread condition affecting both genders, often leading to aesthetic and psychological issues. Traditional treatments like minoxidil and finasteride are effective but can have side effects, prompting interest in plant-based alternatives. This review examines 18 medicinal plants known for hair restoration, detailing their pharmacological actions and key phytoconstituents. It highlights the potential of these bioactive compounds in clinical settings and discusses future trends such as nanotechnology, stem cell therapy, and gene modulation in managing alopecia.