Multifunctional Bioactivity of Saccharomyces Cerevisiae Extracellular Vesicle in Hair Follicle-Related Cellular Models

This study explores the multifunctional bioactivity of extracellular vesicles (EVs) derived from Saccharomyces cerevisiae in hair follicle-related cellular models. The findings reveal that yeast EVs significantly enhance cell viability and metabolic activity in dermal papilla cells, promote keratinocyte wound closure, and exhibit anti-inflammatory properties by reducing IL-1β expression. Additionally, they enhance collagen synthesis and display antioxidant activity, suggesting potential applications in promoting hair follicle activity and maintaining scalp homeostasis. The study highlights the need for further research to validate these effects in vivo and identify specific molecular mediators.