Biochemistry Of Vitamin B: Metabolic Regulations, Deficiency Disorders And Emerging Therapeutic Strategies

The document explores the critical roles of the vitamin B complex in human metabolism, highlighting their function as coenzymes in metabolic processes and their importance in DNA synthesis, energy production, and neurotransmitter synthesis. Deficiencies in these vitamins can lead to severe disorders, including neurological and hematological issues. Emerging therapeutic strategies, such as high-dose pharmacologic approaches and nanotechnology-based carriers, aim to improve absorption and therapeutic potential, expanding the role of B vitamins beyond basic supplementation. The document also discusses the metabolic roles of specific B vitamins, such as niacin, pantothenic acid, pyridoxine, biotin, folate, and vitamin B12, emphasizing their regulatory mechanisms and the impact of deficiencies. Recent advancements in nanotechnology have enhanced vitamin delivery systems, improving stability, absorption, and targeted delivery, which is particularly beneficial for individuals with impaired absorption.