BMP-FGF Signaling Axis Mediates Wnt-Induced Epidermal Stratification in Developing Mammalian Skin

October 2014 in “ PLoS Genetics ”

Xiaojing Zhu, YuDong Liu, Zhong‐Min Dai, Xiaoyun Zhang, Xueqin Yang, Yan Li, Mengsheng Qiu, Jiang Fu, Wei Hsu, Yiping Chen, Zunyi Zhang

We don't know much about this study yet.

We're maintaining the world's largest resposity of hair loss research. You can help out the community by sending a PDF of this study here . Not sure how to get a study's PDF? You can email the authors of the study.

View this study on journals.plos.org →

Discuss this study in the Community →

Research cited in this study

10 / 10 results

research Competitive Balance of Intrabulge BMP/Wnt Signaling Reveals a Robust Gene Network Ruling Stem Cell Homeostasis and Cyclic Activation

176 citations , January 2013 in “Proceedings of the National Academy of Sciences”

BMP and Wnt signaling balance controls hair follicle stem cell activity and hair growth.

Dermal β-Catenin Activity in Response to Epidermal Wnt Ligands Is Required for Fibroblast Proliferation and Hair Follicle Initiation

research Dermal β-Catenin Activity in Response to Epidermal Wnt Ligands Is Required for Fibroblast Proliferation and Hair Follicle Initiation

207 citations , March 2012 in “Development”

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

research KGF And EGF Signaling Block Hair Follicle Induction And Promote Interfollicular Epidermal Fate In Developing Mouse Skin

82 citations , May 2009 in “Development”

EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.

research Embryonic Hair Follicle Fate Change by Augmented Beta-Catenin Through Shh and Bmp Signaling

54 citations , January 2009 in “Development”

β-catenin, Shh, and Bmp signaling control hair follicle development.

research Activation of Beta-Catenin Signaling Programs Embryonic Epidermis to Hair Follicle Fate

193 citations , May 2008 in “Development”

Activating β-catenin can turn skin cells into hair follicles.

research Scratching the Surface of Skin Development

788 citations , February 2007 in “Nature”

The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.

research Defining BMP Functions in the Hair Follicle by Conditional Ablation of BMP Receptor IA

250 citations , November 2003 in “The Journal of Cell Biology”

BMP receptor IA is essential for proper hair cell differentiation in mice.

research Expression and Function of Keratinocyte Growth Factor and Activin in Skin Morphogenesis and Cutaneous Wound Repair

113 citations , December 2000 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings”

KGF and activin are crucial for skin healing and repair.

research Multiple Roles for Activated LEF/TCF Transcription Complexes During Hair Follicle Development and Differentiation

990 citations , October 1999 in “Development”

Activated LEF/TCF complexes are crucial for hair development and cycling.

research Targeting Expression of Keratinocyte Growth Factor to Keratinocytes Elicits Striking Changes in Epithelial Differentiation in Transgenic Mice

265 citations , March 1993 in “The EMBO Journal”

Keratinocyte growth factor significantly alters skin and tissue development.