Association of Breast and Colorectal Cancer in Patients With Central Centrifugal Cicatricial Alopecia: A Retrospective, Cross-Sectional Pilot Study

October 2020 in “ Journal of the American Academy of Dermatology ”

Jessica B. Brown-Korsah, Fritzlaine C. Roche, Susan C. Taylor

central centrifugal cicatricial alopecia CCCA

TLDR Patients with central centrifugal cicatricial alopecia may have a higher risk of breast and colorectal cancer.

The study investigated the potential association between central centrifugal cicatricial alopecia (CCCA) and the risk of breast and colorectal cancer. It was a retrospective, cross-sectional pilot study, which means it looked back at existing data to find patterns or associations. The study aimed to provide preliminary insights into whether patients with CCCA might have an increased risk of developing these types of cancer. However, as a pilot study, it was likely limited in scope and size, serving as a basis for future, more comprehensive research to confirm any findings.

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research Variant PADI3 in Central Centrifugal Cicatricial Alopecia

95 citations , February 2019 in “The New England Journal of Medicine”

Mutations in the PADI3 gene are linked to a higher risk of scarring hair loss in women of African descent.

Permanent Alopecia in Patients with Breast Cancer After Taxane Chemotherapy and Adjuvant Hormonal Therapy: Clinicopathologic Findings in a Cohort of 10 Patients

research Permanent Alopecia in Patients with Breast Cancer After Taxane Chemotherapy and Adjuvant Hormonal Therapy: Clinicopathologic Findings in a Cohort of 10 Patients

31 citations , March 2017 in “Journal of The American Academy of Dermatology”

Some breast cancer patients developed permanent hair loss after chemotherapy and hormonal therapy, showing patterns similar to common baldness and alopecia areata.