TLDR Caffeine from shampoo penetrates hair follicles quickly and stays for at least 24 hours.
The study utilized in vivo laser scanning microscopy to examine the penetration of caffeine from a shampoo into hair follicles. It was found that a 2-minute contact time was sufficient for significant accumulation of caffeine in the follicles, reaching a depth of approximately 200 μm, which is the detection limit of the microscopy used. This depth is where the network of blood capillaries around the follicles begins. Caffeine remained detectable in the follicles even after 24 hours, indicating that hair follicles can serve as a long-term reservoir for topically applied substances like caffeine.
The conversation discusses whether topicalcaffeine is effective for hair loss, with some users questioning its role due to its vasoconstrictive and vasodilative properties, while another suggests that temporary vasoconstriction might be beneficial by promoting angiogenesis. Specific treatments mentioned include caffeine shampoo, which one user believes is ineffective.
Whether topicalcaffeine can be as effective for hair growth as minoxidil and finasteride, with various replies discussing the efficacy of these treatments and criticism of Dr. Huberman's research methods.
Topicalcaffeine is considered ineffective for hair growth, with users favoring minoxidil, finasteride, and dutasteride. Some view it as a scam or only useful for non-responders to other treatments.
The conversation discusses the effectiveness of adding topicalcaffeine serum to a hair loss treatment routine that includes minoxidil and finasteride. Users suggest alternatives like stemoxidine, alphatradiol, and pyrilutamide, noting that evidence for caffeine's effectiveness is weak.
The user is asking if caffeinetopicals are effective for hair growth, noting they already use Minoxidil and finasteride. They are unsure if caffeinetopicals are beneficial or a waste of money.
A user plans to experiment with creating new hairfollicles using methods like derma rolling, applying lithium chloride, tannic acid, and various other substances including caffeine, ketoconazole, and raspberry ketones. They also consider using anti-inflammatories, immunosuppressants, and DHT inhibitors to potentially improve results.
