Cardiovascular Risk Factors in Bulgarian Patients with Polycystic Ovary Syndrome and/or Obesity

    Antoaneta Gateva, Zdravko Kamenov
    TLDR Obese women with PCOS have more cardiovascular risk factors, and waist-to-stature ratio is a better health marker than waist-to-hip ratio.
    The study investigated cardiovascular risk factors in 301 Bulgarian women with polycystic ovary syndrome (PCOS) and/or obesity, divided into three groups: Obese, Lean PCOS, and Obese PCOS. It found that PCOS was associated with insulin resistance and hyperandrogenism, increasing the risk of diabetes and cardiovascular diseases, with obesity exacerbating these risks. The waist-to-stature ratio (WSR) was identified as a better predictor of cardiovascular risk than BMI or waist-to-hip ratio (WHR). Significant differences were observed in metabolic and cardiovascular risk factors between lean and obese PCOS women, with obese individuals showing higher rates of insulin resistance, liver steatosis, and adverse lipid profiles. The study emphasized the importance of early detection and management of these conditions in PCOS patients.
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