TLDR Obese women with PCOS have more cardiovascular risk factors, and waist-to-stature ratio is a better health marker than waist-to-hip ratio.
The study investigated cardiovascular risk factors in 301 Bulgarian women with polycystic ovary syndrome (PCOS) and/or obesity, divided into three groups: Obese, Lean PCOS, and Obese PCOS. It found that PCOS was associated with insulin resistance and hyperandrogenism, increasing the risk of diabetes and cardiovascular diseases, with obesity exacerbating these risks. The waist-to-stature ratio (WSR) was identified as a better predictor of cardiovascular risk than BMI or waist-to-hip ratio (WHR). Significant differences were observed in metabolic and cardiovascular risk factors between lean and obese PCOS women, with obese individuals showing higher rates of insulin resistance, liver steatosis, and adverse lipid profiles. The study emphasized the importance of early detection and management of these conditions in PCOS patients.
60 citations
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April 2003 in “Human Reproduction” Young Czech women with PCOS have a higher risk of heart problems and should be regularly checked for cholesterol and glucose issues.
100 citations
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June 2002 in “Diabetologia”
491 citations
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July 2000 in “The Journal of Clinical Endocrinology and Metabolism” Polycystic ovary syndrome is found in 6.5% of unselected Caucasian women in Spain.
298 citations
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July 2000 in “The Journal of Clinical Endocrinology and Metabolism” About 6.5% of young Caucasian women in Spain have polycystic ovary syndrome.
633 citations
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September 1998 in “The Journal of Clinical Endocrinology and Metabolism” PCOS affects a similar percentage of Black and White women in the Southeastern United States.
378 citations
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September 1998 in “The Journal of Clinical Endocrinology and Metabolism” PCOS affects about 4% of women in the southeastern U.S. equally across Black and White populations.
30 citations
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April 2014 in “Seminars in Reproductive Medicine” Diagnosing PCOS in teenagers is hard because its symptoms often look like normal puberty, and there's a need for better diagnosis methods and agreement on criteria.
1265 citations
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October 2013 in “The Journal of Clinical Endocrinology and Metabolism” The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.
222 citations
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January 2014 in “International journal of reproductive medicine” Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.
258 citations
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July 2016 in “Reproductive Biology and Endocrinology” The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.
1 citations
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June 2023 in “Curēus” PCOS affects nearly 25% of female medical and dental students, impacting their academic and social lives.